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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 330567Generated: October 25, 2026

Dimethyl acetylenedicarboxylate → 1-(3-Methoxy-4-ethoxyphenyl)-2,3-bis(methoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene

https://huagongshe.com/reaction/330567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl acetylenedicarboxylateHCID 12980—
Reactant4-Ethoxy-3-methoxybenzaldehydeHCID 67116—
Reactant2-Bromo-3,4,5-trimethoxybenzaldehyde dimethylacetalHCID 15914458—
Product1-(3-Methoxy-4-ethoxyphenyl)-2,3-bis(methoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthaleneHCID 1391082767%

Reaction Steps

2-Bromo-3,4,5-trimethoxybenzaldehyde dimethyl-acetal, 3-methoxy-4-ethoxybenzaldehyde and dimethyl acetylenedicarboxylate are treated in the same manner as described in Example , whereby 1-(3-methoxy-4-ethoxyphenyl)-2,3-bis(methoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene is obtained as colorless needles.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04897418
Source datasetuspto-grants-1990_01
ORD IDord-3da3f408530545cf81c1f1cd45241b9d
Source noteuspto-grants-1990_01