2-Chloro-6-fluorobenzaldehyde → N-[(2-chloro-6-fluorophenyl)methyl]cyclopropanamine

HRID 33057Notes

Reaction equation

HRID 33057 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([F:10])[C:3]=1[CH:4]=O.[CH:11]1([NH2:14])[CH2:13][CH2:12]1>>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([F:10])[C:3]=1[CH2:4][NH:14][CH:11]1[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 678472-Chloro-6-fluorobenzaldehydeHCID 69828Cyclopropylamine

Product 1

HCID 4720324N-[(2-chloro-6-fluorophenyl)methyl]cyclopropanamine

Procedure

Synthesized according to typical procedure J from 2-chloro-6-fluorobenzaldehyde and cyclopropylamine.

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-4dd9bd80c5ab4d66befedf2a29e79644
Source dataset
uspto-grants-2008_09
Patent number
US07427613B2

Reaction notes

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