4-Nitrobenzyl chloride → HCID 14127927, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 34.4 g (0.2 mole) of 4-nitrobenzyl chloride and 27.9 g (0.3 mole) of 4-methylpyridine in 200 ml of acetonitrile is refluxed for 8 hours. The solution is evaporated down to about half its volume and cooled to 0° C., and the precipitate which separates out is filtered off under suction, washed thoroughly with ether and dried under reduced pressure to give 37.6 g (71% of theory) of the title compound of melting point 220°-222° C.

Provenance & Evidence