Pentanal → HCID 5370211, compound

Participants

Reaction Steps

To 200 mL (170.4 g, 2.40 mol) of rapidly stirred pyrrolidine at 3° C., under argon, was added 100 g (0.72 mmol) of potassium carbonate followed by 127 mL (102.9 g, 1.19 mol) of valeraldehyde dropwise over 75 min. After stirring at 3°-5° C. for 6 hr, the suspension was stored at ca. 0° C. for 64 hr, filtered and the collected solids were washed with 2×50 mL of anhydrous ether. The combined filtrates were concentrated in vacuo and the residue was distilled to give 142.32 g (85.7%) of N-[1-(E)-penten-1-yl]pyrrolidine, bp 54°-56° C. (0.6-0.7 mm Hg).

Provenance & Evidence