Methyl iodide → HCID 131716292, compound

Participants

Reaction Steps

To 29 mg (0.06 mmol) of VII in 5 ml of chloroform was added 1 ml of methyliodide. After the mixture was stirred for 24 hours at room temperature, the solvent and alkylating agent were removed in vacuo to afford a thick orange oil. Crystallization from ethanol-ether produced 36 mg (90% yield), of a finely divided yellow powder: mp 135° C. decomposes; Rf(E)=0.06. Analysis calculated for C24H27N4O4I: C, 51.26; H, 4.84; N, 9.96. Found: C, 50.05; H, 5.23; N, 9.85. Fast atom bombardment mass spectrum: calculated for MW (435)+I-. Found: 435 (M+).

Provenance & Evidence