Cyclopropylamine → (2-Chloro-3,6-difluorobenzyl)cyclopropylamine
Reaction equation
[Cl:1][C:2]1[C:9]([F:10])=[CH:8][CH:7]=[C:6]([F:11])[C:3]=1[CH:4]=O.[CH:12]1([NH2:15])[CH2:14][CH2:13]1>>[Cl:1][C:2]1[C:9]([F:10])=[CH:8][CH:7]=[C:6]([F:11])[C:3]=1[CH2:4][NH:15][CH:12]1[CH2:14][CH2:13]1Participants
3
Procedure
Synthesized according to typical procedure J from 2-chloro-3,6-difluorobenzaldehyde and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-e3cbfb62284b4152b5a81daf834fe092
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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