Cyclopropylamine → Cyclopropyl-(3-trifluoromethoxybenzyl)amine
Reaction equation
[F:1][C:2]([F:13])([F:12])[O:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O.[CH:14]1([NH2:17])[CH2:16][CH2:15]1>>[CH:14]1([NH:17][CH2:7][C:6]2[CH:9]=[CH:10][CH:11]=[C:4]([O:3][C:2]([F:13])([F:12])[F:1])[CH:5]=2)[CH2:16][CH2:15]1Participants
3
Procedure
Synthesized according to typical procedure J from 3-trifluoromethoxy-benzaldehyde and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-3429250f182a44cdabdab5896b3afb77
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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