HCID 14724008, compound → HCID 14723828, compound

HRID 330687Notes

Reaction equation

HRID 330687 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:36]2[CH:41]=[CH:40][C:39]([F:42])=[CH:38][CH:37]=2)=[C:9]([C:12]2[N:13]=[N:14][N:15]([C:17]([C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[N:16]=2)[CH2:10][OH:11])=[CH:4][CH:3]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:36]2[CH:41]=[CH:40][C:39]([F:42])=[CH:38][CH:37]=2)=[C:9]([C:12]2[N:13]=[N:14][N:15]([C:17]([C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)[N:16]=2)[CH:10]=[O:11])=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 14724008HCID 14724008, compound

Product 1

HCID 14723828HCID 14723828, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Procedure

To a solution of 2.2 g (4.0 mmol) 3,3-bis(4-fluorophenyl)-2-[2-(triphenylmethyl)-2H-tetrazol-5-yl]-2-propenol in 100 mL methylene chloride was added 7 g of activated manganese dioxide. After stirring the resultant mixture for 20 hours, the insolubles were removed by filtration and the filtrate concentrated in vacuo to give a quantative yield of the title compound; m.p.=208° C. (dec).

Workup

  1. customthe insolubles were removed by filtration
  2. concentrationthe filtrate concentrated in vacuo

Sources & evidence

ORD record
ord-adf6fcac1ead4692ad72a5fc52e0ee42
Source dataset
uspto-grants-1990_01
Patent number
US04897490

Reaction notes

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