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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33070Generated: October 25, 2026

Cyclopropyl-(2,3-dichloro-benzyl)-amine → (rac.)-(1R*,5S*)-3-Acetyl-7-{4-[2(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid cyclopropyl-(2,3dichlorobenzyl)amide formate salt

https://huagongshe.com/reaction/33070

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropyl-(2,3-dichloro-benzyl)-amineHCID 834599—
Reactant3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo-[3.3.1]non-6-ene-6,9-dicarboxylic acid 9-(2,2,2-trichloro-1,1-dimethylethyl) esterHCID 67420793—
Product(rac.)-(1R*,5S*)-3-Acetyl-7-{4-[2(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid cyclopropyl-(2,3dichlorobenzyl)amide formate saltHCID 131727067—

Reaction Steps

Synthesized according to typical procedures H and E from bicyclononene BN10 and cyclopropyl-(2,3-dichlorobenzyl)amine. LC-MS: Rt=0.92; ES+: 672.22.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427613B2
Source datasetuspto-grants-2008_09
ORD IDord-430ae3daa1824bbc9da4585a0aa8c0d5
Source noteuspto-grants-2008_09