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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33073Generated: October 29, 2026

N-(2-chlorobenzyl)cyclopropanamine → (rac.)-(1R*,5S*)-3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid (2-chlorobenzyl)-cyclopropylamide formate salt

https://huagongshe.com/reaction/33073

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-chlorobenzyl)cyclopropanamineHCID 834606—
Reactant3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo-[3.3.1]non-6-ene-6,9-dicarboxylic acid 9-(2,2,2-trichloro-1,1-dimethylethyl) esterHCID 67420793—
Product(rac.)-(1R*,5S*)-3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid (2-chlorobenzyl)-cyclopropylamide formate saltHCID 131727070—

Reaction Steps

Synthesized according to typical procedures H and E from bicyclononene BN10 and (2-chlorobenzyl)cyclopropylamine. LC-MS: Rt=0.90; ES+: 638.22.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427613B2
Source datasetuspto-grants-2008_09
ORD IDord-5fb8eae6519d403584c1ba3e615159ff
Source noteuspto-grants-2008_09