HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropyl-(2-fluoro-5-methoxybenzyl)amine → (rac.)-(1R*,5S*)-3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid cyclopropyl-(2-fluoro-5-methoxybenzyl)amide formate salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropyl-(2-fluoro-5-methoxybenzyl)amine | HCID 66783902 | — |
| Reactant | 3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo-[3.3.1]non-6-ene-6,9-dicarboxylic acid 9-(2,2,2-trichloro-1,1-dimethylethyl) ester | HCID 67420793 | — |
| Product | (rac.)-(1R*,5S*)-3-Acetyl-7-{4-[2-(2-chloro-5-fluorophenoxy)ethoxy]phenyl}-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxylic acid cyclopropyl-(2-fluoro-5-methoxybenzyl)amide formate salt | HCID 131727071 | — |
Reaction Steps
Synthesized according to typical procedures H and E from bicyclononene BN10 and cyclopropyl-(2-fluoro-5-methoxybenzyl)amine. LC-MS: Rt=0.88; ES+: 652.26.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427613B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-ab93c5d4cd9d4f52a38b04505faf7f66 |
| Source note | uspto-grants-2008_09 |