HRID33075

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4721137

N-(3-methoxybenzyl)cyclopropanamine

C11H15NO

结构：CC(=O)N1CC2CC(c3ccc(OCCOc4cc(F)ccc4Cl)cc3)=C(C(=O)O)C(C1)N2C(=O)OC(C)(C)C(Cl)(Cl)Cl

HCID67420793

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(CN(C(=O)C2=C(c3ccc(OCCOc4cc(F)ccc4Cl)cc3)C[C@@H]3CN(C(C)=O)C[C@H]2N3)C2CC2)c1.O=CO

HCID131727072

未命名化合物

PROCEDURE

实验过程

Synthesized according to typical procedures H and E from bicyclononene BN10 and cyclopropyl-(3-methoxybenzyl)amine. LC-MS: Rt=0.87; ES+: 634.27.

WORKUP

后处理

customSynthesized

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0058e4e6341647e79ecc31b856bf2b2e
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07427613B2
来源说明: uspto-grants-2008_09

反应 SMILES

ClC(Cl)(Cl)C([O:6][C:7]([N:9]1[CH:14]2[C:15]([C:36](O)=[O:37])=[C:16]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH2:26][O:27][C:28]4[CH:33]=[C:32]([F:34])[CH:31]=[CH:30][C:29]=4[Cl:35])=[CH:20][CH:19]=3)[CH2:17][CH:10]1[CH2:11][N:12]([C:39](=[O:41])[CH3:40])[CH2:13]2)=[O:8])(C)C.[CH:44]1([NH:47][CH2:48][C:49]2[CH:54]=[CH:53][CH:52]=[C:51]([O:55][CH3:56])[CH:50]=2)[CH2:46][CH2:45]1>>[CH:7]([OH:8])=[O:6].[CH:44]1([N:47]([CH2:48][C:49]2[CH:54]=[CH:53][CH:52]=[C:51]([O:55][CH3:56])[CH:50]=2)[C:36]([C:15]2[C@@H:14]3[NH:9][C@H:10]([CH2:17][C:16]=2[C:18]2[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH2:26][O:27][C:28]4[CH:33]=[C:32]([F:34])[CH:31]=[CH:30][C:29]=4[Cl:35])=[CH:20][CH:19]=2)[CH2:11][N:12]([C:39](=[O:41])[CH3:40])[CH2:13]3)=[O:37])[CH2:46][CH2:45]1