HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-methoxy-N-methyl-2-nitroaniline → 3-methoxy-N1-methylbenzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-methoxy-N-methyl-2-nitroaniline | HCID 58071591 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-methoxy-N1-methylbenzene-1,2-diamine | HCID 10606936 | 95.4% |
Reaction Steps
7.4 g (3-methoxy-2-nitrophenyl)-methylamine are suspended in 150 ml of ethyl acetate and hydrogenated with 1 g Pd/C 10% at a pressure of 50 psi and ambient temperature. After 4.5 hours the catalyst is suction filtered and the filtrate is evaporated to dryness. 5.9 g of the product are obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877758B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-625595317ec14a42abdfa01e88c6f1b6 |
| Source note | uspto-grants-2014_11 |