Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 69216515, compound

HRID 33091Notes

Reaction equation

HRID 33091 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([N+:9]([O-])=O)[CH:6]=[CH:5][C:4]=1[NH:12][CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:33].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:33].[ClH:33].[NH2:9][C:7]1[CH:6]=[CH:5][C:4]([NH:12][CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)=[C:3]([O:2][CH3:1])[CH:8]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104829N-(2-methoxy-4-nitrophenyl)-N-(2-pyrid-2-ylethyl)amine

Product 1

HCID 69216515HCID 69216515, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The N-(2-methoxy-4-nitrophenyl)-N-(2-pyrid-2-ylethyl)amine (9) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-134e436a10f64f738c44f53b104b67a9
Source dataset
uspto-grants-2008_09
Patent number
US07429278B2

Reaction notes

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