Pyrrolidine → HCID 178516811, compound

Participants

Reaction Conditions

Reaction Steps

In a 5 mL microwave vial, 6-chloro-4-pyridazinol (D46) (76 mg, 0.582 mmol) was dissolved in pyrrolidine (1 ml, 12.09 mmol). The reaction mixture was stirred for 30 min at 130° C. in a microwave. The reaction mixture was loaded onto the MDAP for purification (acidic conditions). The desired product recovered was triturated with DCM (1×3 mL) to afford the title compound (65 mg). LCMS (A): m/z (M+H)+ 166, C8H11N3O requires 165 (acidic).

Provenance & Evidence