HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71090239, compound → HCID 71090066, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 71090239 | HCID 71090239 | — |
| Reactant | HCID 71090294 | HCID 71090294 | — |
| Product | HCID 71090066 | HCID 71090066 | — |
Reaction Steps
Example 135 was separated by chiral chromatography to give two enantiomers: (R)N-(1-(1-methylpyrrolidin-3-yl)-3-(3-(pyrrolidin-1-yl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)benzenesulfonamide and (S)N-(1-(1-methylpyrrolidin-3-yl)-3-(3-(pyrrolidin-1-yl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)benzenesulfonamide. The absolute stereochemistry was not determined LCMS (A): m/z (M+H)+ 502, C28H31N5O2S requires 501 (acidic).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877742B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-a5a9aec99ba54990b7c81f5d5ccbbeb2 |
| Source note | uspto-grants-2014_11 |