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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33120Generated: October 26, 2026

1,2-dihydro-4-(4-ethylbenzyl)-5-methyl-3H-pyrazol-3-one → 4-[(4-Ethylphenyl)methyl]-3-(beta-D-glucopyranosyloxy)-5-methyl-1H-pyrazole

https://huagongshe.com/reaction/33120

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-dihydro-4-(4-ethylbenzyl)-5-methyl-3H-pyrazol-3-oneHCID 11984072—
Reactant4-[(4-Ethylphenyl)methyl]-5-methyl-3-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyloxy)-1H-pyrazoleHCID 67335578—
Product4-[(4-Ethylphenyl)methyl]-3-(beta-D-glucopyranosyloxy)-5-methyl-1H-pyrazoleHCID 9907776—
Product4-[(4-Ethylphenyl)methyl]-5-methyl-3-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyloxy)-1H-pyrazoleHCID 67335578—

Reaction Steps

4-[(4-Ethylphenyl)methyl]-5-methyl-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-1H-pyrazole was prepared in a similar manner to that described in Reference Example 17 using 4-[(4-ethylphenyl)methyl]-1,2-dihydro-5-methyl-3H-pyrazol-3-one instead of 1,2-dihydro-4-[(4-isopropoxyphenyl)methyl]-5-methyl-3H-pyrazol-3-one. Then, the title compound was prepared in a similar manner to that described in Reference Example 37 using 4-[(4-ethylphenyl)methyl]-5-methyl-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-1H-pyrazole instead of 4-[(4-isopropoxyphenyl)methyl]-5-methyl-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)-1H-pyrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429568B2
Source datasetuspto-grants-2008_09
ORD IDord-70464759235447209bc343cf28fff4c7
Source noteuspto-grants-2008_09