HuagongsheHuagongshe Chemistry Print Report · For research reference only
T5637827 → 3-(4-Fluorophenyl)-2,3-dihydro-6-hydroxyinden-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | T5637827 | HCID 5356382 | — |
| Reactant | (E)-3-(4-fluorophenyl)-1-(3-hydroxyphenyl)prop-2-en-1-one | HCID 6258426 | — |
| Product | 3-(4-Fluorophenyl)-2,3-dihydro-6-hydroxyinden-1-one | HCID 70304861 | 47% |
Reaction Steps
The procedure of Step 2 of Example 1 was repeated except for using (E)-3-(4-fluorophenyl)-1-(3-hydroxyphenyl)prop-2-en-1-one obtained in Step 1 as a starting material instead of (E)-1-(3-hydroxyphenyl)-3-phenylprop-2-en-1-one, being stirred for 5 d, and removing TFA by rotary evaporation to obtain the title compound (47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-eefde60a489b432c9b0a7f32fcc95c8a |
| Source note | uspto-grants-2014_11 |