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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 331306Erstellt: 25. Oktober 2026

2-(Dimethylamino)ethanol → 6-(2-(Dimethylamino)ethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one

https://huagongshe.com/reaction/331306

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-(Dimethylamino)ethanolHCID 7902—
Edukt2-bromo-6-hydroxy-3-phenyl-1H-inden-1-oneHCID 70306176—
Edukt6-Hydroxy-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-oneHCID 70313190—
Produkt6-(2-(Dimethylamino)ethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-oneHCID 5100183545%

Reaktionsschritte

The procedure of Step 6 of Example 1 was repeated except for using 6-hydroxy-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one obtained in Step 1 of Example 55 as a starting material instead of 2-bromo-6-hydroxy-3-phenyl-1H-inden-1-one, 2-(dimethylamino)ethanol instead of 4-(2-hydroxyethyl)morpholine, and being recrystallized with EtOAc to obtain the title compound (45%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08877747B2
Quelldatensatzuspto-grants-2014_11
ORD IDord-299228a248794e1a9ec82e0398d18846
Quellennotizuspto-grants-2014_11