Quinoline-3-boronic acid → HCID 51002237, compound

Participants

Reaction Steps

The procedure of Step 7 of Example 1 was repeated except for using 2-bromo-3-(3,5-difluorophenyl)-6-[2-(1,1-dioxothiomorpholin-4-yl)ethoxy]-1H-inden-1-one obtained in Step 1 as a starting material instead of 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one, 3-quinolinylboronic acid instead of 3-pyridinylboronic acid and being purified by silica gel column chromatography (acetone/hexanes=1:3) to obtain the title compound (95%).

Provenance & Evidence