HuagongsheHuagongshe Chemistry Print Report · For research reference only
Quinoline-3-boronic acid → HCID 67639464, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Quinoline-3-boronic acid | HCID 2734663 | — |
| Reactant | 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one | HCID 70307620 | — |
| Reactant | 2-Bromo-3-(2,4-difluorophenyl)-6-[2-(1,1-dioxothiomorpholin-4-yl)ethoxy]-1H-inden-1-one | HCID 70314038 | — |
| Product | HCID 67639464 | HCID 67639464 | 74% |
Reaction Steps
The procedure of Step 7 of Example 1 was repeated except for using 2-bromo-3-(2,4-difluorophenyl)-6-[2-(1,1-dioxothiomorpholin-4-yl)ethoxy]-1H-inden-1-one obtained in Step 1 of Example 112 as a starting material instead of 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one and 3-quinolinylboronic acid instead of 3-pyridinylboronic acid to obtain the title compound (74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-f55e771194f2452ea42fa38de5a18674 |
| Source note | uspto-grants-2014_11 |