HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one → 5-Hydroxy-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one | HCID 70310041 | — |
| Reactant | 3-(3,5-Difluorophenyl)-5-methoxy-2-(pyridin-3-yl)-1H-inden-1-one | HCID 70313614 | — |
| Product | 5-Hydroxy-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one | HCID 70312804 | 93% |
Reaction Steps
The procedure of Step 5 of Example 128 was repeated except for using 5-methoxy-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one obtained in Step 5 as a starting material instead of 3-(3,5-difluorophenyl)-5-methoxy-2-(pyridin-3-yl)-1H-inden-1-one to obtain the title compound (93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-7fd35b31067f4262b92a672057e47cc0 |
| Source note | uspto-grants-2014_11 |