HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Pyridin-4-yl)boronic acid → 5-Methoxy-3-phenyl-2-(pyridin-4-yl)-1H-inden-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Pyridin-4-yl)boronic acid | HCID 2734379 | — |
| Reactant | 2-Bromo-5-methoxy-3-phenyl-1H-inden-1-one | HCID 10470936 | — |
| Reactant | 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one | HCID 70307620 | — |
| Product | 5-Methoxy-3-phenyl-2-(pyridin-4-yl)-1H-inden-1-one | HCID 70315915 | 74% |
Reaction Steps
The procedure of Step 7 of Example 1 was repeated except for using 2-bromo-5-methoxy-3-phenyl-1H-inden-1-one obtained in Step 4 of Example 129 as a starting material instead of 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one, 4-pyridinylboronic acid instead of 3-pyridinylboronic acid, and being stirred for 10 min to obtain the title compound (74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-5d4184d1f2964f98a9bce7b6e5762a6b |
| Source note | uspto-grants-2014_11 |