HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tolylboronic acid → 5-Methoxy-3-phenyl-2-(p-tolyl)-1H-inden-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tolylboronic acid | HCID 79799 | — |
| Reactant | 2-Bromo-5-methoxy-3-phenyl-1H-inden-1-one | HCID 10470936 | — |
| Reactant | 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one | HCID 70307620 | — |
| Product | 5-Methoxy-3-phenyl-2-(p-tolyl)-1H-inden-1-one | HCID 70312872 | 70% |
Reaction Steps
The procedure of Step 7 of Example 1 was repeated except for using 2-bromo-5-methoxy-3-phenyl-1H-inden-1-one obtained in Step 4 of Example 129 as a starting material instead of 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one, p-tolylboronic acid instead of 3-pyridinylboronic acid, and being stirred for 10 min to obtain the title compound (70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-1d6f4e9e214f4dd58f2bdf4dfb93b846 |
| Source note | uspto-grants-2014_11 |