2-Methanesulfonylacetic acid → HCID 178504896, compound

Participants

Reaction Steps

The title compound, off-white solid (101 mg, 90%), MS (ISP) m/z=449.3 [(M+H)+], mp 211° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 2-methanesulfonyl-acetic acid.

Provenance & Evidence