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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331421Generated: October 28, 2026

2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → HCID 178425857, compound

https://huagongshe.com/reaction/331421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-1,2-oxazol-5-yl)acetic acidHCID 4195532—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178425857HCID 178425857—

Reaction Steps

The title compound, off-white solid (107 mg, 95%), MS (ISP) m/z=452.4 [(M+H)+], mp 188° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 2-(3-methylisoxazol-5-yl)-acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-c60ee97902394aa9abdcf5883a86e778
Source noteuspto-grants-2014_11