Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331427Generated: October 31, 2026

Cyclobutanecarboxylic acid → HCID 178523584, compound

https://huagongshe.com/reaction/331427

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanecarboxylic acidHCID 19494—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178523584HCID 178523584—

Reaction Steps

The title compound, white solid (81 mg, 79%), MS (ISP) m/z=411.4 [(M+H)+], mp 197° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and cyclobutanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-232bbadb200b4d1da2a46d88d5743427
Source noteuspto-grants-2014_11