Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331429Generated: October 30, 2026

1-Hydroxy-1-cyclopropanecarboxylic acid → HCID 178523605, compound

https://huagongshe.com/reaction/331429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Hydroxy-1-cyclopropanecarboxylic acidHCID 2733160—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178523605HCID 178523605—

Reaction Steps

The title compound, white solid (70 mg, 68%), MS (ISP) m/z=413.5 [(M+H)+], mp 164° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 1-hydroxy-cyclopropane-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-7b8ab170cbef4af6a5f2731a3b8f5b7b
Source noteuspto-grants-2014_11