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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331430Generated: October 30, 2026

Cyclopropanecarboxylic acid → HCID 178523582, compound

https://huagongshe.com/reaction/331430

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarboxylic acidHCID 15655—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178523582HCID 178523582—

Reaction Steps

The title compound, off-white solid (72 mg, 73%), MS (ISP) m/z=397.4 [(M+H)+], mp 208° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and cyclopropanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-10aaff9e253742f2be15ac74148c02cc
Source noteuspto-grants-2014_11