Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331434Generated: October 30, 2026

4-(Morpholin-4-yl)benzoic acid → HCID 178523597, compound

https://huagongshe.com/reaction/331434

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Morpholin-4-yl)benzoic acidHCID 345278—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178523597HCID 178523597—

Reaction Steps

The title compound, light yellow solid (97 mg, 75%), MS (ISP) m/z=518.4 [(M+H)+], mp 247° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 4-(morpholine-4-yl)-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-4f97ca6f63f3489aa070baf2ab12d677
Source noteuspto-grants-2014_11