HCID 2779071, compound → HCID 178520775, compound

Participants

Reaction Steps

The title compound, white solid (84 mg, 72%), MS (ISP) m/z=469.4 [(M+H)+], mp 189° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and (R)-4,4,4-trifluoro-3-hydroxy-butyric acid.

Provenance & Evidence