HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,3-Trifluoro-2-hydroxypropanoic acid → HCID 178523607, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,3-Trifluoro-2-hydroxypropanoic acid | HCID 244896 | — |
| Reactant | HCID 178478710 | HCID 178478710 | — |
| Product | HCID 178523607 | HCID 178523607 | — |
Reaction Steps
The title compound, yellow solid (39 mg, 35%), MS (ISP) m/z=455.4 [(M+H)+], mp 179° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and (RS)-3,3,3-trifluoro-2-hydroxy-propionic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877778B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-d999be66f3ca49cbadce0f0f7ee622fe |
| Source note | uspto-grants-2014_11 |