HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Isobutoxy-5-methanesulfonyl-benzoic acid → (4-Benzoxazol-2-yl-piperazin-1-yl)-(2-isobutoxy-5-methanesulfonyl-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Isobutoxy-5-methanesulfonyl-benzoic acid | HCID 23503110 | — |
| Reactant | 2-(Piperazin-1-yl)benzo[d]oxazole hydrochloride | HCID 66570214 | — |
| Product | (4-Benzoxazol-2-yl-piperazin-1-yl)-(2-isobutoxy-5-methanesulfonyl-phenyl)-methanone | HCID 11683962 | — |
Reaction Steps
Prepared in analogy to example 1.1 b) from 2-isobutoxy-5-methanesulfonyl-benzoic acid (Example 2.4) and 2-piperazin-1-yl-benzoxazole hydrochloride. The crude material was purified by chromatography (SiO2, ethyl acetate) to yield the title compound as a slightly yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429585B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-6f7e969f69684394aa018b7e1b8a7fca |
| Source note | uspto-grants-2008_09 |