Ethanesulfonyl chloride → HCID 178477727, compound

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Reaction Steps

The title compound, white solid (41 mg, 39%), MS (ISP) m/z=421.2 [(M+H)+], mp 131° C., was prepared in accordance with the general method of example 47 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and ethanesulfonyl chloride.

Provenance & Evidence