4-Fluorobenzenesulfonyl chloride → HCID 178527578, compound

Participants

Reaction Steps

The title compound, white solid (84 mg, 69%), MS (ISP) m/z=487.4 [(M+H)+], mp 134° C., was prepared in accordance with the general method of example 47 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydro chloride (intermediate B) (100 mg, 0.25 mmol) and 4-fluoro-benzenesulfonyl chloride.

Provenance & Evidence