Cyanoacetic acid → HCID 178511188, compound

Participants

Reaction Steps

The title compound, light yellow solid (75 mg, 76%), MS (ISP) m/z=396.3 [(M+H)+], mp 194° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 2-cyano-acetic acid.

Provenance & Evidence