2-cyclobutylacetic Acid → HCID 178520160, compound

Participants

Reaction Steps

The title compound, off-white solid (53 mg, 50%), MS (ISP) m/z=425.3 [(M+H)+], mp 196° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydro chloride (intermediate B) (100 mg, 0.25 mmol) and 2-cyclobutyl-acetic acid.

Provenance & Evidence