2-Methylbutanoic Acid → HCID 178447378, compound

Participants

Reaction Steps

The title compound, off-white solid (84 mg, 82%), MS (ISP) m/z=413.5 [(M+H)+], mp 210° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and (RS)-2-methyl-butyric acid.

Provenance & Evidence