Tetrahydropyran-4-ylacetic acid → HCID 178520326, compound

Participants

Reaction Steps

The title compound, off-white solid (76 mg, 65%), MS (ISP) m/z=471.4 [(M+H)+], mp 187.5° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(7-fluoro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate C) (104 mg, 0.25 mmol) and tetrahydropyran-4-yl-acetic acid.

Provenance & Evidence