4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 178432521, compound

Participants

Reaction Steps

The title compound, white solid (98 mg, 77%), MS (ISP) m/z=515.4 [(M+H)+], mp 256.5° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydro chloride (intermediate B) (100 mg, 0.25 mmol) and 4-(5-methyl-[1,2,4]oxadiazol-3-yl)-benzoic acid.

Provenance & Evidence