6-Quinolinecarboxylic acid → HCID 178523586, compound

Participants

Reaction Steps

The title compound, white solid (107 mg, 89%), MS (ISP) m/z=484.5 [(M+H)+], mp 238° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and quinoline-6-carboxylic acid.

Provenance & Evidence