trans-3-pentenoic acid → HCID 178447374, compound

Participants

Reaction Steps

The title compound, white solid (77 mg, 75%), MS (ISP) m/z=411.4 [(M+H)+], mp 196° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and (E)-pent-3-enoic acid.

Provenance & Evidence