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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331491Generated: October 30, 2026

(1,1'-Biphenyl)-4-carboxylic acid → HCID 178523587, compound

https://huagongshe.com/reaction/331491

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178523587HCID 178523587—

Reaction Steps

The title compound, white solid (112 mg, 88%), MS (ISP) m/z=509.5 [(M+H)+], mp 241° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and biphenyl-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-9eb45fe2d8a6485fac6053e471d6ae6f
Source noteuspto-grants-2014_11