Benzo-1,3-dioxole-5-acetic acid → HCID 178520182, compound

Participants

Reaction Steps

The title compound, white solid (112 mg, 92%), MS (ISP) m/z=491.3 [(M+H)+], mp 209° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 2-benzo[1,3]dioxol-5-yl-acetic acid.

Provenance & Evidence