p-(Methylsulphonyl)benzoic acid → HCID 178504771, compound

Participants

Reaction Steps

The title compound, white solid (104 mg, 82%), MS (ISP) m/z=511.4 [(M+H)+], mp 236° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 4-methanesulfonyl-benzoic acid.

Provenance & Evidence