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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33166Generated: October 28, 2026

Hydrochloric Acid → 2-(Piperazin-1-yl)quinoline hydrochloride

https://huagongshe.com/reaction/33166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-Butyl 4-(quinolin-2-yl)piperazine-1-carboxylateHCID 16117834—
Solvent1,4-DioxaneHCID 31275—
Product2-(Piperazin-1-yl)quinoline hydrochlorideHCID 52988159—

Reaction Steps

Prepared in analogy to example 1.6(d) from 4-quinolin-2-yl-piperazine-1-carboxylic acid tert.-butyl ester and dioxane saturated with gaseous hydrochloric acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429585B2
Source datasetuspto-grants-2008_09
ORD IDord-9b8eb1198af64e018cea5de63d2828e8
Source noteuspto-grants-2008_09