HuagongsheHuagongshe Chemistry Print Report · For research reference only
Alanine, ethyl ester, hydrochloride (1:1) → HCID 68444993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Alanine, ethyl ester, hydrochloride (1:1) | HCID 102560 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 66599213 | — |
| Product | HCID 68444993 | HCID 68444993 | 17% |
Reaction Steps
As described for example 15, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using DL-alanine ethylester hydrochloride instead of 3-methoxypropylamine, to the title compound (23 mg, 17%) which was obtained as a light yellow gum. MS: m/e=410.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877782B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-2cd2d8034b734ea0980bad9da35a25f4 |
| Source note | uspto-grants-2014_11 |