HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Piperazin-1-yl-quinoline hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Quinolin-3-yl-piperazine-1-carboxylic acid tert.-butyl ester | HCID 58906302 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-Piperazin-1-yl-quinoline hydrochloride | HCID 68895919 | — |
Reaction Steps
Prepared in analogy to example 1.6(d) from 4-quinolin-3-yl-piperazine-1-carboxylic acid tert.-butyl ester and dioxane saturated with gaseous hydrochloric acid. Yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429585B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-610ad79f76ed4f59851ace7a802e4ab9 |
| Source note | uspto-grants-2008_09 |