HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → (2-Isopropoxy-5-methanesulfonyl-phenyl)-(4-quinolin-3-yl-piperazin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| Reactant | 3-Piperazin-1-yl-quinoline hydrochloride | HCID 68895919 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (2-Isopropoxy-5-methanesulfonyl-phenyl)-(4-quinolin-3-yl-piperazin-1-yl)-methanone | HCID 58906311 | — |
Reaction Steps
Prepared in analogy to example 1.1(b) from 3-piperazin-1-yl-quinoline hydrochloride and 2-isopropoxy-5-methanesulfonyl-benzoic acid (example 2.2) in acetonitrile. Chromatography (SiO2; ethyl acetate) yields the title compound as a colorless foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429585B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-e3b97f0bd7c149abbe683d04eef3a725 |
| Source note | uspto-grants-2008_09 |