HRID331824

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22309060

Ethyl 3-(3-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate

C13H12FNO3

HCID22309061

Ethyl 3-(4-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate

C13H12FNO3

PRODUCTS

生成物

HCID28473136

[3-(4-Fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanol

C11H10FNO2

收率 72.4%

PROCEDURE

实验过程

As described for example 88d, 3-(4-fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester (3.0 g, 12 mmol) was converted, instead of 3-(3-fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester, to the title compound (1.8 g, 71%) which was obtained as a white solid. MS: m/e=208.1 [M+H]+.